Application of Mixed Hydrotropic Solubilization in Spectrophotometric Estimation of Aceclofenac in Tablets
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منابع مشابه
Application of Hydrotropic Solubilization in Spectrophotometric Estimation of Lornoxicam from Tablets
Lornoxicam is a selective cyclooxygenase-1 and cyclooxygenase-2 inhibitor that exhibits anti-inflammatory, analgesic, and antipyretic activities. It is used in osteoarthritis and rheumatoid arthritis; and in treatment of postoperative pain and primary dysmenorrhoea. Lornoxicam is completely insoluble in water but soluble in alkaline solutions. Hydrotropic solubilization is a technique used to i...
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Two simple, accurate and precise methods for simultaneous estimation of Esomeprazole and Itopride in bulk drug and tablet dosage form have been described. Method-A employs formation and solving of simultaneous equation using 231 and 370 nm as two analytical wavelengths. Method -B is Absorption ratio method, which uses 308 and 331 nm as two analytical wavelengths.Beer’s law was obeyed in the con...
متن کاملFormulation and Evaluation of Aceclofenac Injection Made by Mixed Hydrotropic Solubilization Technique
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that exhibits analgesic, antipyretic and anti-inflammatory activities. It is practically insoluble in water. The effect of hydrotropes such as urea and sodium citrate and blends (urea + sodium citrate) on the solubility of aceclofenac was investigated. The enhancement in the solubility of aceclofenac was more than 5 and 25 folds in 3...
متن کاملFormulation and Evaluation of Aceclofenac Injection Made by Mixed Hydrotropic Solubilization Technique
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that exhibits analgesic, antipyretic and anti-inflammatory activities. It is practically insoluble in water. The effect of hydrotropes such as urea and sodium citrate and blends (urea + sodium citrate) on the solubility of aceclofenac was investigated. The enhancement in the solubility of aceclofenac was more than 5 and 25 folds in 3...
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ژورنال
عنوان ژورنال: Journal of Current Pharma Research
سال: 2011
ISSN: 2230-7834,2230-7842
DOI: 10.33786/jcpr.2011.v01i03.001